Learn More About Products Made With DII

As with all chemicals, precautions are in place to help protect the persons handling methylene diphenyl diisocyanate (MDI) and toluene diisocyanate (TDI) during production, transportation, or processing of the chemical. The following offers resources developed to provide information on handling, storing and transporting MDI and TDI, including their use in making polyurethane foams. There are also helpful resources for the transportation of chemicals in general.

Materials Handling

CPI’s Documents
The Center for the Polyurethanes Industry (CPI) has developed a number of documents to assist with the safe handling and storage of TDI, MDI, and related polyurethane materials, including:

  • Equipment Guidelines for Diisocyanate Storage Tanks
    This Technical Bulletin is intended to provide guidelines for describing various equipment options for storage tank systems intended for diisocyanate product service. The Bulletin includes a reference table of equipment options, which is supplemented by additional text. (AX-365, 2016) | (Spanish) 

NIOSH Pocket Guide
The National Institute for Occupational Safety and Health (NIOSH) published a Pocket Guide to Chemical Hazards. The pocket guides for MDI and TDI available here: 4,4'-MDI Listing and 2,4-TDI Listing.


CPI has developed information about the safe transportation of TDI and MDI, including:

Other Transportation Resources

  • Transport Canada, provides oversight and gives expert advice on dangerous goods accidents to promote public safety in the transportation of dangerous goods by all modes of transport in Canada. Visit Transport Canada for information about regulations for the transportation of dangerous goods (TDG) and more.